CPSA USA 2017

Enabling Personalized Medicine:
Connecting People, Disciplines and Technology

Preliminary Program     Monday | Tuesday | Wednesday | Thursday

Updated July 21, 2017

Monday OCTOBER 23

7:30 am - 8:30 am
Princeton Foyer

Registration Open


Short Courses

All short courses are held at the Sheraton Bucks County Hotel

8:30 AM - 4:00 PM Princeton I

Protein Identification, Quantification, and Biomarker Analysis
Instructors: Nalini Sadagopan, Agilent Technologies; Nathan Yates, University of Pittsburgh

8:30 AM - 4:00 PM Princeton II

Bioanalysis of Mix Modalities via Hybrid and Orthogonal Approaches
Instructors: Suzanne Cordovado, CDC; Barry Jones, Q2 Solutions; Linlin Luo, Bristol-Myers Squibb; Jim Shen, Bristol-Myers Squibb

8:30 AM - 4:00 PM
Lehigh

Building a Better Clinical Mass Spectrometry Lab
Instructors: Don Chace, Medolac Laboratories; Tim Garrett, University of Florida; Mark Hayward, Active Ingredient Technologies; Kenneth Lewis, OpAns

8:30 AM - 4:00 PM LaSalle

Human Pharmacokinetic Prediction and Approaches to Identify Rate Determining Step of Drug Absorption and Elimination: Industrial Perspective
Instructors: Ayman El-Kattan, Pfizer; Yurong Lai, Gilead

12:00 pm - 4:00 pm
University Grille

Microsampling and Patient Centric Sampling – A journey through what it is and how you can incorporate it into your workflows
Instructors: Neil Spooner, Spooner Bioanalytical Solutions; Joe Siple, New Objective

7:30 am - 9:30 am
Tyler State Park
Newtown, PA

CPSA Charity 5K Event

Contact Nicole Matz for more information.
Organizers: Nicole Matz, PRA Health Science; Guowen Liu, Agios; Naidong Weng, Janssen Research & Development; Helen Weng, Frontage Laboratories

10:00 am - 3:00 pm
Makefield Highlands Golf Club, Yardley, PA

CPSA Open Charity Golf Event

Organizers:John Butler, Agilent Technologies; Paul Corcoran, McKinley Scientific; Clark Williard, inVentiv Health Clinical Lab

12:00 pm - 4:00 pm
Villanova Amphitheater

Advanced Training in MassMetaSite / WebMetabase / MassChemSite Structure Elucidation Tools

Discussion Leaders: Ismael Zamora, Molecular Discovery

12:00 pm - 4:00 pm
Princeton I/II

Joint ACS Meeting

4:30 pm - 5:30 pm
University I/II

Executive Roundtable
Where Technology and Solutions Meet Business

Discussion Leaders: Lucinda R. Hittle, Merck; Emily Ehrenfeld, Mozaic Solutions

6:00 pm - 9:00 pm
University I/II

Reception & Sponsor's Dinner

Opening Remarks

CPSA Charitable Foundation
Paul Corcoran, McKinley Scientific; Emily Ehrenfeld, New Objective

CPSA Institute
Naidong Weng, Janssen Research & Development; Tim Garrett, University of Florida

Distinguished Lecture Series

Tuesday OCTOBER 24

7:30 am - 8:30 am
University Foyer

Registration & Continental Breakfast

8:30 am - 9:00 am
University I/II

Welcome & Opening Remarks

Opening Remarks – Disease is the Enemy!

Mike Lee

Welcome
Mike S. Lee
Milestone Development Services

Suzanne Cordovado

Format, Objectives, Opening Remarks
Suzanne Cordovado
Centers for Disease Control and Prevention

Emily Ehrenfeld


Emily Ehrenfeld
New Objective

9:00 am - 9:45 am
University I/II

Plenary Lecture

Kyriakie Sarafoglou

Screening, Diagnosis and Treatment of Newborns with Congenital Adrenal Hyperplasia:
Opportunities for Improvements
Kyriakie Sarafoglou
University of Minnesota

10:00 am - 11:45 am

Parallel Sessions

Princeton I

TRACK I: Symposium Session

Informatics in the Clinical Laboratory
Discussion Leader: Timothy Garrett, University of Florida

Princeton II

TRACK II: Colloquium Session

Session Title to Be Announced

Discussion Leader: Chad Briscoe, PRA Health Services

Villanova

TRACK III: Colloquium Session

Session Title to Be Announced

Discussion Leader: To Be Announced

12:00 pm - 1:00 pm
University I/II

Sponsored Lunch & Roundtables

1:00 pm - 3:00 pm
University Foyer

Poster Session & Roundtables

Discussion Leaders: Mark Cancilla, Merck; Helene Cardasis, Thermo Fisher Scientific; Scoot Hottenstein, GlaxoSmithKline; Wenkui Li, Novartis; Enaksha Wickremsinhe, Eli Lilly & Co.; Matthew Szapacs, GlaxoSmithKline

3:15 pm - 4:45 pm

Parallel Sessions

University I

TRACK IV:Symposium Session

Marriage of Biochemistry and Molecular:
Clarifying or Confusing

Discussion Leaders: Don Chace, Medolac Laboratories; Suzanne Cordovado, Centers for Disease Control and Prevention

University II

TRACK V-a - Colloquium Session

Importance of Chromatography in Applied Sciences – Current Trends, Education, and Career Opportunities

Discussion Leaders (on behalf on Chinese American Chromatography Association): Yi He, John Jay College of Criminal Justice, CUNY & Naidong Weng, Janssen Research & Development

This colloquium session consists of podium presentations from both academia and industry. This session will highlight the importance of chromatography on applied sciences and the current trends. We will also discuss how to strengthen the chromatography education, training and career advance opportunities. Chinese American Chromatography Association, a volunteer-based non-profit organization, plays important role to promote and educate chromatography sciences among young scientists.

Advantages of Superficial Porous Particles in Chromatography
Chuping Luo, Advanced-Materials-Tech

Current Applications and New Trends of Liquid Chromatography – Mass Spectrometry in Forensic Toxicology
Marta Concheiro-Gisan, John Jay College, NY

Applying Chromatography to Resolve Real-world Pharmaceutical Challenges – A 30 Year Journey of An Accidental Chromatographer
Naidong Weng, Janssen Reasearch & Development

Villanova

TRACK V-b - Colloquium Session

Bioanalytical Considerations in Biological Therapeutics

Discussion Leaders: Sophia Xu, Bristol-Myers Squibb and Weifeng Xu, Bristol-Myers Squibb

LC-MS for Biologics
Yang Xu, Merck

Biosimilars
Xiaoyan Cai, Wuxi AppTec

Reagents
Jonathan Haulenbeek, Bristol-Myers Squibb

Immunogenicity
Sharon Arrol, Alexion

Neutralizing Antibody Assay
Weifeng Xu, Bristol-Myers Squibb

Lehigh

TRACK V-c - Colloquium Session

Structure Identification

Discussion Leaders: David Detlefsen, Novatia and Mark Hail, Novatia

4:45 pm - 5:15 pm
2nd Floor Lobby

Let Them Eat Cake!

Donald Chace, Medolac Laboratories

5:00 pm - 6:00 pm
 

Social Hour & Sponsored Workshops

Princeton I

WORKSHOP

Princeton II

WORKSHOP

Villanova

WORKSHOP
Patient Centric Blood Sampling and Analysis: What is it and will it become a reality?

Current approaches to the collection of blood samples for the quantitative determination of analytes are not fit for purpose. They are often inconvenient for patients, expensive for health systems and pharmaceutical companies and wasteful of the sample collected. This Workshop will highlight emerging technologies that could change this paradigm. Participants will discuss whether these approaches will warrant acceptance in the future for the generation of high quality data for clinical decision making. Various criteria will be considered including: Is the approach realistic? What technologies will we need? How might we better integrate high quality sampling with high quality analysis and data reporting, etc.?

6:30 pm - 9:00 pm pm

Sponsor Hospitality & Evening Workshops

University I

Microsampling Summit

Workshop Leaders: Qin Ji, Bristol-Myers Squibb and Olga Kavetskaia, Pfizer

University II

Workshop

Wednesday OCTOBER 25

7:30 am - 8:30 am
University Foyer

Registration & Continental Breakfast

7:30 am - 8:30 am
University I/II
8:30 am - 10:00 am

Symposium Session & Roundtables

Development of New Biomarkers: A Focus on Disease Progression Biomarkers

Discussion Leader: Alla Kloss, Genzyme

10:15 am - 11:45 am

Parallel Sessions

Villanova Amphitheater

TRACK VI: Symposium Session

Symposium Session: A Bird’s Eye View from the Top: Analysis of Intact Proteins by Mass Spectrometry for In-Life Sample Sets

Discussion Leaders: Wenying Jian, Janssen Research & Development; John Kellie, GlaxoSmithKline

Princeton I/II

TRACK VII-a:Colloquium Session

Innovation in the Modern Bioanalysis Lab

Discussion Leader: Lucinda Hittle, Merck

Lehigh

TRACK VII-b:Colloquium Session

Metabolite Identification and Databases: Industrial Workflows and Emerging Trends

Discussion Leader: Ismael Zamora, Molecular Discovery

LaSalle

TRACK VII-c:Colloquium Session

Patient Centric Blood Sampling and Analysis: Let’s Make this Happen!

Discussion Leader: Neil Spooner, Spooner Bioanalytical Solutions; Joe Siple, New Objective

Following-on from Tuesday evening's workshop, this Colloquium will bring together technology companies and thought leaders that are interested in positively moving forwards the agenda and expediting the time frame for developing and establishing patient centric blood sampling and analysis approaches with the public, media, regulators, etc., in order to increase the likelihood of acceptance of these technologies and the data arising from them.

12:00 pm - 1:00 pm
 

Sponsored Lunch & Roundtable

1:15 pm - 2:15 pm
 

Social Hour & Sponsored Workshops

Princeton I

WORKSHOP

Princeton II

WORKSHOP

Villanova

WORKSHOP

Lehigh

WORKSHOP

2:30 pm - 3:30 pm

Parallel Sessions

University II

Innovator Award Session

Discussion Leaders: Mark Cancilla, Merck and Daniel Spellman, Merck

Villanova Ampitheatre

Steven A. Hofstadler Graduate Student Session

Inspiring Career Paths in the Sciences for Young Scientists

Discussion Leader: Petia Shipkova, Bristol-Myers Squibb

Student Presentations

Online Hydrophobic Interaction Chromatography-Mass Spectrometry for Top-down Protein Analysis
Bifan Chen, University of Wisconsin

Characterization of Protein-Protein Interactions by Protein Cross-linking Capillary Electrophoresis
Claire Ouimet, University of Michigan

TBA
Peter Doubleday, Northwestern University

An Integrative Approach for Determining Biomarkers and Etiology of a Disease Leading to Mass Die Offs of Aquatic Life in South Africa
Jeremy Koelmel, University of Florida

Mentors:
Sue Abbatiello, Thermo Fisher Scientific
Brad Ackermann, Eli Lilly and Company
Don Chace, Medolac Laboratories
Paul Corcoran, McKinley Scientific
Emily Ehrenfeld, New Objective
Lucinda Hittle, Merck
Jonathan Josephs, Thermo Fisher Scientific
Alla Kloss, Genzyme
Kenneth Lewis, OpAns
Eric Milgram, PepsiCo
Shane Needham, Alturas Analytics
Timothy Olah, Bristol-Myers Squibb
Joanna Pols, Regeneron Pharmaceuticals
Suma Ramagiri, SCIEX
Robyn Rourick, Genentech
Petia Shipkova, Bristol-Myers Squibb
James Small, Merck
Anthony Yeung, Fox Chase Cancer Center

3:45 pm - 4:15 pm
Princeton I/II

CPSA Announcements & Award Presentations

Local ACS Discussion Groups

CPSA Europe
Neil Spooner, Spooner Bioanalytical Solutions
Ismael Zamora, Molecular Discovery

CPSA Metabolomics
Timothy Garrett, University of Florida

CPSA Shanghai
Naidong Weng, Janssen Research & Development

CPSA Analytics
Nathan Yates, University of Pittsburgh

CPSA BRASIL
Carla Marshall-Waggett, New Objective
Martin Steel, McKinley Scientific

Innovator Award Presentation
Mark Cancilla, Merck
Daniel Spellman, Merck

Steven A. Hofstadler Graduate Student Award/Recognition
Emily Ehrenfeld, New Objective
Petia Shipkova, Bristol-Myers Squibb

Program Chair Recognition
Mike Lee, Milestone Development Services

CPSA USA 2018 Program Chair
Suzanne Cordovado, Centers for Disease Control & Prevention
Emily Ehrenfeld, New Objective

4:15 pm - 5:45 pm

Keynote Dinner Lectures

Keynote Lecture

Carla Cuthbert


Carla Cuthbert, Centers for Disease Control and Prevention


Distinguished Analytical Scientist Award

Binodh DeSilva


Biondh DeSilva
Bristol-Myers Squibb

5:45 pm - 6:45 pm
University I & Lobby

Exhibition & Social Hour

6:45 pm - 9:00 pm
University II

Vendor Session - Five Minutes of Fame (5MOF)!

Discussion Leaders: Mark Hayward, ITSP; Nicole Donnelly, PharmaCadence Analytical Services; Matt Szapacs, GlaxoSmithKline

Thursday OCTOBER 26

7:30 am - 8:30 am
2nd Floor Lobby

Registration & Continental Breakfast

8:30 am - 10:00 am
Princeton I/II

Colloquia & Roundtables

Collaborative Research Models Between Pharma and CRO

Discussion Leader: Jim Shen, Bristol-Myers Squibb

10:15 am - 11:45 am

Parallel Sessions

Villanova

TRACK VIII: Symposium Session

Discussion Leader: Robyn Rourick, Genentech

Lehigh

TRACK IX: Colloquium Session

Traditional and Non-Traditional Strategies to Generate Drug Metabolites for Analytical Characterization

Discussion Leader: James Small, Merck

12:00 pm - 1:15 pm

Sponsored Lunch & Roundtables

1:30 pm - 3:00 pm
Princeton I/II

Symposium Session & Roundtables

Presentations from the Edge: Young Scientists Session
Discussion Leader: Roy Vaz, Sanofi and Alla Kloss, Sanofi

1:30 pm - 3:00 pm
Villanova

Symposium Session & Roundtables

Alternative Instrumentation
Discussion Leaders: Kevin Bateman, Merck and Rick King, PharmaCadence Analytical Services

3:00 pm

Adjourn